The self-evaluation meeting for the conclusion of the medical and health science and technology

On June 16, 2021, the summary and task review meeting of the project "Mechanism of Occurrence and Intervention of Adverse Blood Transfusion Reactions" of the Medical and Health Science and Technology Innovation Project of Chinese Academy of Medical Sciences was successfully held in the Academic Hall of Peking Union Medical College Hospital. The review experts attending this meeting were Professor Liu Kaiyan, Deputy Director of the Institute of Hematology, Peking University, Professor Jiang Yu, School of Group Medicine and Public Health, Peking Union Medical College, Professor Wang Deqing, First Medical Center, PLA General Hospital, and Professor Zhan Linsheng, Institute of Health Service and Blood Transfusion, Institute of Military Medical Research, Academy of Military Sciences. Project team members Prof. Huang Yuguang, Director of Department of Anesthesiology, Peking Union Medical College Hospital, Prof. Liu Zhong, Deputy Director of Institute of Blood Transfusion, Prof. Ji Hongwen, Director of Department of Blood Transfusion, Fu Wai Hospital, Prof. Bai Lianjun, Deputy Chief Technologist and Gan Jia, Deputy Director of Department of Blood Transfusion, Peking Union Medical College Hospital, Dr. Zhao Guohua, Deputy Chief Physician and Li Xiying, Deputy Director of Department of Blood Transfusion, Cancer Hospital, and Ge Hongwei, Director of Beijing Red Cross Blood Center, as well as the main research backbone of each unit of the project team and Some students, totaling more than 20 people, attended the review meeting. The meeting was chaired by Deputy Director Gan Jia and Deputy Director Li Xiying.

The review meeting started with a brief introduction of the overall progress of the project by Prof. Liu Zhong, the project leader. From the establishment of the project in 2016 to now, the project team has accomplished a lot of work in sincere cooperation, established the China Adverse Blood Transfusion Reaction Research Consortium, received support from peers nationwide, and set up sub-consortiums in five provinces of Jilin, Yunnan, Guangxi, Liaoning, and Inner Mongolia. Since the blood transfusion adverse reaction reporting system has been online, the transfusion adverse reaction research alliance has been established to study the mechanism of adverse reaction occurrence and development and intervention strategies. Its results are applied to clinical practice, recognized and supported by the government and industry, and written into the development of national norms and national standards and expert consensus. In addition, the team has participated in the development of APEC Blood Safety 2020 Roadmap, penned the National Blood Safety Report, researched and submitted research reports such as "Blood Screening Strategy in China", developed national health industry standards such as "Use of Whole Blood and Component Blood" and "Blood Component Preparation Technology", trained several graduate students, and published nearly 100 papers, etc.

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After that, the three subtask leaders reported on the completion and results of the subtasks. Associate Professor Jue Wang reported the research results of Task 1 on blood transfusion adverse reaction prevention and control technologies and strategies, which achieved the following results: systematic establishment of blood group genotyping detection technology system; research on the risk and mechanism of blood group-related alloimmune antibody production; research on the quality evaluation system of blood products such as plasma and coagulation factors; and research on the evaluation of pathogen-related infectious blood transfusion adverse reactions and screening strategies.

Presentation by Associate Professor Jue Wang

Dr. Guohua Zhao, deputy chief physician, reported on the development of the China Adverse Blood Transfusion Reaction Research Consortium and the reporting of adverse reaction data on Task 2, focusing on the standard development and quality control of the adverse reaction reporting system, and introduced the important socio-economic benefits of this task.

Dr. Guohua Zhao, deputy chief physician, gave a presentation

Prof. Hongwen Ji made a report on Task 3 Patient Blood Management and Precision Transfusion Research, in which clinical researchers used the research results on the development mechanism of adverse reactions to carry out clinical practice and application research, developed expert consensus, obtained good clinical results, and successfully transformed into national norms and standards under the care and support of the national health administration and standards committees.

Prof. Ji Hongwen gave a presentation

After the report of each sub-task, the experts highly affirmed the important achievements and main achievements of each sub-task. At the same time, guiding opinions and suggestions are also provided for the shortcomings and reporting methods of each sub-task. Experts pointed out that the content of the report should be simplified, the main results should be highlighted, and the published articles should be further summarized, analyzed and refined to improve clinical practice.

Professor Liu Kaiyan made a comment

Professor Jiang Yu made a comment

Professor Wang Deqing made a comment

Professor Zhan Linsheng made a comment

Finally, Director Huang Yuguang made a summary. Director Huang Yuguang highly affirmed the social significance of the results and outputs of this project. At the same time, Director Huang also emphasized that while publishing articles in scientific research, it is also necessary to solve various problems of clinical blood use. Through the cooperation of clinical blood quality control centers and cooperative units in various places, we will promote the safety of clinical blood use and improve the practice of clinical blood transfusion. , which truly reflects the principle that scientific research serves clinical services.

Summary by Professor Huang Yuguang

The meeting was hosted by the Peking Union Medical College Hospital of the Chinese Academy of Medical Sciences. The team members fully exchanged and cooperated, and further discussed the cooperation projects to be carried out during the 14th Five-Year Plan period to jointly promote the improvement of the national blood safety level.